Kirkland Signature Glucosamine Overall Review: 3 out of 5.

Two active ingredients in this formula are widely known in the jointKirkland Signature Glucosamine (with chondroitin sulfate) is a formula intended to help people who suffer from rheumatoid arthritis or osteoarthritis – or any other joint/degenerative conditions.-health community; they are glucosamine and chondroitin sulfate. These two ingredients are often found sold as individual supplements or – in this case – together.

Glucosamine is an amino sugar found in the connective tissues of the body. An ideal world, our bodies will produce enough glucosamine in our joints will have no problems. However, we are constantly “punishing” our bodies with daily wear and tear; especially those who lead active, athletic lifestyles. In these cases, it would be beneficial if our bodies could produce more glucosamine to even things out. Unfortunately, it doesn’t really work that way. The thought is that we may be able to supplement our bodies with glucosamine that is typically derived from shellfish, and this will fill in the gaps. If we do not get enough glucosamine, our joints can be in for some serious problems.

It is not uncommon glucosamine paired with chondroitin sulfate. Chondroitin itself, like glucosamine, is an essential component of our connective tissues – especially concerning joint cartilage and bones. Chondroitin is needed – it is thought – to promote the way that collagen absorbs shock, as well as to inhibit some of the enzymes that attempt to break the cartilage down. It also may help the cartilage retain the water that it needs to promote elasticity and flexibility. One of the main reasons that are paired so often with glucosamine is that these two working together are thought to actually reverse the process of cartilage loss, rebuilding this connective tissue.

While more studies certainly need to be done on the effects of glucosamine and chondroitin – as well as other naturally-occurring supplements for joints – many prefer this approach to prescription medication, as these ingredients are largely thought to be safe, non-toxic, and side-effects free.

Kirkland offers some variations on these products, which some containing the sulfur known as MSM.

Kirkland Signature Glucosamine Benefits:

– may help with arthritis pain
– may reverse the process of cartilage loss

Kirkland Signature Glucosamine Negatives:

– contains only two ingredients
– require some dedication

Kirkland Signature Glucosamine Ingredients:

– Glucosamine
– Chondroitin Sulfate

Clinical Studies: 

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